I have Ubuntu running nicely on my PC and the new screen and it looks good! My PC isn't great under Linux, as it seems to drag its heels at times. Though it's not a new PC, it's not that old!
I must say the combination of the wide screen, Drivel (for posting to my blog), Epiphany (browser) and other Gnome/Linux apps is actually quite nice. Audio under Ubuntu (and implicitly other Linux distrubutions) is rather embarrassing given how long Linux and Gnome have been around. I use Native Instrument's Guitar Rig 2, with a USB device for audio and MIDI input & output. It works just fine.. well almost. I can only use one audio app at a time. For example, if I'm listening to music I can't get any audio notifications from Gnome. Not a big deal, but this isn't 1980 any more people!
I think there's another (not another one!) new audio system called PulseAudio but I have no idea if GR2 works with it.